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Due to their relatively high plasma levels at the time of meal intake, the short-acting GLP-1 mimetics relative to the long-acting GLP-1R agonists display a higher tendency to affect GI motility and to decrease post-prandial hyperglycemia (74)
The copper ion is essential to GHK-Cu's biological activity
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Int J Nanomed
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![Mechanism of action of GLP-1 [25]](https://www.researchgate.net/profile/Asfandyar-Sheikh/publication/256289222/figure/fig1/AS:614177232142337@1523442671231/Mechanism-of-action-of-GLP-1-25.png)
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