Neuronale Zeroidlipofuszinose 12 (NCL-12) Einzelanalyse Clinical signs are non-specific and

Clinical signs are non-specific and include abdominal pain

This phenotype is called agouti (wolf grey or wolf sable)

The disease typically starts before 10 months of age

It is characterized by degeneration of the cerebellar structures

Neuronale Zeroidlipofuszinose 12 (NCL-12) Einzelanalyse Clinical signs are non-specific andNeuronal ceroid lipofuscinoses (NCLs) are a group of heritable diseases characterized by progressive neuronal degeneration and accumulation of autofluorescent cytoplasmic inclusions in the brain, retina and other tissues. Clinical symptoms and progress of the disease include increased rates of irritability, with the possibility of outbursts of aggression, hallucinations, hyperactivity and seizures. Most animals lose their ability to coordinate